Cisco and NVIDIA Unveil Breakthrough Innovations to Power the Next Generation of AI Infrastructure
The announcements, made in collaboration with NVIDIA and industry partners, mark a significant step forward in redefining data center, enterprise, and telecom architectures for the AI era.
Cisco has unveiled a series of major innovations designed to accelerate the global deployment of secure, scalable artificial intelligence (AI) infrastructure. The announcements, made in collaboration with NVIDIA and industry partners, mark a significant step forward in redefining data center, enterprise, and telecom architectures for the AI era.
At the center of the announcement is the Cisco N9100, the first NVIDIA partner-developed data center switch based on NVIDIA Spectrum-X Ethernet switch silicon. The switch will serve as the foundation for NVIDIA Cloud Partner-compliant reference architectures, enabling both neocloud and sovereign cloud deployments. This advancement positions Cisco as a key enabler of high-performance, open, and energy-efficient networking for AI workloads.
The Cisco Secure AI Factory with NVIDIA introduces enhanced protection and visibility for enterprise AI deployments. Through new security and observability integrations — including Cisco AI Defense with NVIDIA NeMo Guardrails and Splunk Observability Cloud — enterprises can now monitor AI workloads in real time, protect sensitive data, and ensure compliance across distributed environments.
Cisco also introduced new infrastructure capabilities within its AI Factory architecture. Cisco AI PODs, powered by Cisco Silicon One, now support inference workloads with validated Kubernetes networking through Cisco Isovalent. Meanwhile, the Nexus Hyperfabric AI system and UCS 880A M8 rack servers with NVIDIA HGX B300 GPUs expand compute capacity for AI training, inference, and fine-tuning applications.
In a landmark move for telecommunications, Cisco and NVIDIA — joined by industry partners — unveiled the first AI-native wireless stack for 6G networks. The innovation integrates sensing and communication technologies into mobile infrastructure, paving the way for advanced 5G services and next generation 6G applications. The solution combines Cisco’s 5G core software and user plane function with the NVIDIA AI Aerial platform, enabling intelligent, secure, and high-efficiency mobile networks built for the AI-driven future.
These developments are part of Cisco’s broader vision to deliver open, interoperable, and secure AI ecosystems. By combining NVIDIA Spectrum-X Ethernet, Silicon One, and BlueField-4 DPUs across its Nexus switching portfolio, Cisco enables organizations to scale AI infrastructure with flexibility and operational simplicity.
Industry experts have praised Cisco’s unified approach to AI networking, noting its ability to simplify deployment across enterprises, neoclouds, and service providers. The new solutions also align with Cisco’s commitment to energy efficiency, network openness, and operational scalability, helping customers balance innovation with sustainability.
With these advancements, Cisco and NVIDIA are shaping the future of AI infrastructure — from cloud data centers and enterprises to telecom networks — ensuring that AI systems of tomorrow are faster, safer, and more intelligent than ever before.
