HPE Expands NVIDIA AI Portfolio to Revolutionize Enterprise AI Deployment
Leveraging deep co-engineering with NVIDIA, HPE now offers an advanced portfolio of integrated and validated systems designed to accelerate AI adoption while addressing scale, security, and governance requirements.
Hewlett Packard Enterprise has announced a major expansion of its NVIDIA AI Computing by HPE portfolio, aiming to redefine how enterprises deploy, operationalize, and scale AI. Leveraging deep co-engineering with NVIDIA, HPE now offers an advanced portfolio of integrated and validated systems designed to accelerate AI adoption while addressing scale, security, and governance requirements.
“The AI race is fundamentally about speed, scale, and trust. Our industry leadership across cloud, networking, and AI enables organizations to operationalize AI securely, efficiently, and at an unprecedented scale. Together with NVIDIA, HPE delivers turnkey AI factories and networks that transform AI ambitions into real enterprise value.”
– Antonio Neri, president and CEO, HPE
“NVIDIA and HPE are setting a new standard for enterprise AI infrastructure. HPE’s leadership across private cloud, networking, and secure on-prem systems uniquely positions them to make AI a core enterprise capability. Together, we are building AI factories and AI grids — foundational infrastructure to embed intelligence into every workflow.”
– Jensen Huang, founder and CEO, NVIDIA
HPE is expanding its HPE Private Cloud AI, a turnkey enterprise AI factory co-engineered with NVIDIA, to deliver improved performance, scalability, and flexibility for enterprise inferencing. Organizations including the Ryder Cup, Danfoss, and the Dallas Cowboys are leveraging HPE Private Cloud AI to accelerate transformative AI initiatives. New network expansion racks enable deployments of up to 128 GPUs, while air-gapped configurations provide fully isolated, secure deployments.
The company is also enhancing security for enterprise AI through certifications such as Fortanix Confidential AI and partnerships with CrowdStrike, enabling secure on-premises AI model deployment and AI-powered threat detection. HPE Private Cloud AI now features pre-configured hardware and software stacks with the latest NVIDIA AI Enterprise software, updated NVIDIA AI-Q blueprint for AI agents, and NVIDIA Omniverse blueprint for digital twins. Support for NVIDIA Nemotron open models and RTX PRO 6000 Blackwell Server Edition GPUs further strengthens scalable, secure infrastructure.
In addition, HPE is introducing new AI solutions across retail, medical research, and manufacturing, combining HPE ProLiant servers with NVIDIA accelerated computing, Spectrum-X networking, and advanced software stacks. The new NVIDIA RTX PRO 4500 Blackwell Server Edition GPU targets edge deployments, small-language models, vector databases, and data analytics workloads, including integration with the NVIDIA Retail Shopping Assistant Blueprint.
HPE also showcased networking solutions at NVIDIA GTC 2026, aimed at connecting distributed AI deployments for service providers, sovereigns, and large enterprises. The company expanded its at-scale AI factories built on the NVIDIA Vera Rubin architecture to handle the most demanding AI workloads.
To optimize AI data pipelines, HPE is enhancing the HPE Alletra MP X10000 to accelerate every stage of AI workloads, achieving NVIDIA-Certified Storage validation for object-based systems at the Foundation level, and supporting the NVIDIA STX rack-scale reference architecture for new AI storage solutions.
HPE Services is offering a new agents hub to standardize adoption of agentic AI, developing reusable patterns powered by NVIDIA Nemotron™ models. Additionally, HPE Financial Services launched a 90/9 Advantage financing program, providing no payments for 90 days followed by monthly lease payments of 1 percent for nine months, across networking, hybrid cloud, and compute server portfolios.
Availability: Support for NVIDIA RTX PRO 4500 Blackwell GPUs on HPE ProLiant servers will roll out in Q1–Q2 2026. HPE Private Cloud AI with air-gapped deployments, RTX PRO 6000 Blackwell GPU support, and NVIDIA AI-Q and Omniverse blueprints is available immediately. Network expansion racks scaling up to 128 GPUs will be available in July 2026. The secure blueprint for multi-tenant AI factories with Protopia is planned for Q2 2026.
